From Foundation (1951)
(Dr. Seldon is on trial):
Q. You quibble, Dr. Seldon. Can the overall history of the human race be changed?
A. Yes.
Q. Easily?
A. No. With great difficulty.
Q. Why?
A. The psychohistoric trend of a planet-full of people contains a huge intertia. To be changed it must be met with something possessing a similar inertia. Either as many people must be concerned, or if the number of people be relatively small, enormous time for change must be allowed. Do you understand?

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